Ketamine for Chronic Pain
Ketamine has emerged as a promising treatment for depression, particularly for those who haven’t responded to traditional antidepressants. Unlike conventional medications that can take weeks to show effects, ketamine often provides rapid relief, sometimes within hours or days. Research indicates that about 70% of patients with treatment-resistant depression see improvement with ketamine infusion therapy, and 30-40% may experience complete remission of symptoms.
How does ketamine work to help Chronic Pain
Analgesic Properties: Ketamine is well-known for its analgesic properties and has been used as an anesthetic for decades. It can provide rapid pain relief, which is particularly useful in emergency settings where immediate pain management is required.
Mechanism and Benefits: Ketamine’s action on NMDA receptors helps in reducing pain by blocking the transmission of pain signals in the brain. This can be beneficial for patients with chronic pain conditions who have not responded to other pain management strategies.
Clinical Applications: Ketamine is used in various forms, including IV infusions and nasal sprays, to manage chronic pain. Its ability to provide rapid and effective pain relief makes it a valuable tool in the emergency department.